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The antimicrobial effects of essential oils have been reported in the scientific literature, especially regarding the essential oil of Melaleucaalternifolia, also known as tea tree essential oil (TTO). This essential oil has antiseptic properties and can represent a natural-product alternative for hand hygiene in health-care settings which currently use mainly products based on triclosan and chlorhexidine.

Comparison of hand hygiene antimicrobial efficacy: Melaleucaalternifolia essential oil versus triclosan versus chlorhexidine