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The emergence and spread of resistance in Enterobacteriaceae are complicating the treatment of serious nosocomial infections and threatening to create species resistant to most currently available antimicrobial agents. Extended spectrum β-lactamase (ESBL)-producing Enterobacteriaceae causing nosocomial infection pose unique challenges to clinical microbiologists, clinicians, infection control professionals and antibacterial-discovery scientists in Nepal.

Extended spectrum-beta-lactamase producing Enterobacteriaceae causing nosocomial infection in a tertiary care hospital, Nepal