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Klebsiella pneumoniae is one of the most common nosocomial bloodstream infection (BSI) pathogens in neonatal intensive care units (NICUs) of developing countries. Its ability to produce extended-spectrum beta-lactamases (ESBLs) has caused great concern worldwide. Early studies reported that high beta-lactam antibiotic consumption was an independent risk factor for acquisition of ESBL-producing K. pneumoniae BSI.

antimicrobial resistance and infection control

P094: Impact of antibiotics changes on the incidence of bloodstream infection due to extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in an Algerian neonatal intensive care unit