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receive antiviral treatment during the pandemic than during the post-pandemic seasons (89.7% vs. 75.7%, p<0.001). A higher proportion of adults admitted to the ICU during the 2009 pandemic (94.2%) received antiviral treatment compared with the 2010-11 and 2011-12 seasons (84.6%, p<0.001). There was no difference in antiviral treatment among inpatients who died within 30 days of admission during the pandemic (84.3%) than during the post-pandemic seasons (78.9%, p=0.370). Conclusion Antiviral treatment of adults hospitalized with laboratory-confirmed influenza significantly fell in the two seasons following the 2009 influenza pandemic. In order to guide strategies aimed at minimizing the impact of influenza among hospitalized adults, reasons for the decline in antiviral treatment need to be further explored.

P041: Trends in antiviral use in hospitalized patients following the 2009 influenza pandemic in Canada