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In Finland, incidence of CDI increased during 2002-2006, shown by the population-based analysis of hospital discharge diagnoses, a trend similar to that in the US. In 2008, toxin-positive C. difficile became a notifiable disease. During the first 3 years of surveillance, the annual incidence decreased from 111 to 90/100,000 population, but rose up to 100 in 2011. The epidemic situation and trends differed regionally. Both PPI and FQ use have been associated with increased risk of CDI.

antimicrobial resistance and infection control

P029: Regional differences in Clostridium difficile infections (CDI) in relation to fluoroquinolone (FQ) and proton pump inhibitor (PPI) use, Finland, 2008-2011