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During antibiotic treatments a fraction of the dose impacts the intestinal microbiota, promoting spread of resistant bacteria (RB). Antibiotics can be inactivated by adsorption. DAV132 is an oral medical device to deliver an adsorbent in the late ileum. We investigated if DAV132 could reduce fecal antibiotics and RB excreted.

O012: Can DAV132, a medical device targeting an adsorbent to the late ileum, decrease significantly the impact of antibiotics on the fecal microbiota?