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Scientific object The epidemic diffusion of diabetes mellitus has raised serious concerns about the deleterious effects of its complications. Diabetic retinopathy (DR) is a severe progressive ocular pathology and the leading cause of blindness in adults. There is a significant limitation in specific biomarkers for DR, thus, implying that DR diagnosis occur when vision is already compromised. Poor glycemic control, with elevated hemoglobin A1c (HbA1c), and hypertension are recognized risk factors, however the implication of inflammatory processes in DR pathogenesis has prompt interest in the identification of biomarkers of disease within the immune system.

Validation of biomarkers of diabetic retinopathy for preventing and predictive medicine in diabetic complications