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Materials and methods In this diagnostic test study, the type 2 diabetic patients were submitted to clinical and laboratory evaluation. Endothelial function was evaluated with Doppler ultrasound of the brachial artery, measuring the basal diameter and the FMD after ischemia in the forearm. ROC curves were constructed and two scores were used as reference standards to assess the risk of having a cardiovascular event over 10 yrs.: UKPDS risk engine (<10%=low risk and ≥ 10%=high risk) and ASCVD (<7.5%=low risk and ≥ 7.5% =high risk). The cutoff points of basal diameter and FMD were determined based on the equilibrium between sensitivity (S) and specificity (E).

Evaluation of brachial artery diameter and flow-mediated vasodilatation as tools to predict cardiovascular events in type 2 diabetes patients