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Background Diabetes mellitus (DM) is an endocrine and metabolic disease that can cause alterations in platelet function [1]. Extracellular nucleotides such as ATP, ADP and adenosine are important in modulating processes linked to inflammation and thrombosis[2]. Diabetes-mediated changes in immune status may render patients more prone to fungal infections such as those caused by Candida spp[3]. The interest in developing nanostructured systems for improving the bioavailability and protection from physical and chemical degradation of herbal medicinal products has increased significantly.

diabetology and metabolic syndrome

Aqueous seed extract of Syzygium cumini (asc) and polymeric nanoparticles (npasc) modulate adenine nucleotide and nucleoside hydrolysis in diabetic rats with candidiasis