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Purpose of the study In Vietnam, treatment failure to first-line ART, and the decision to switch patients to second-line ART, is usually made on the basis of clinical and immunological criteria because viral load (VL) testing has just been performed since June 2007. However, many studies have shown that these criteria have very low sensitivity and specificity. We estimated the rate of virological failure (VF), and predictors in HIV patients with clinical and/or immunological failure to first-line regimens in Ho Chi Minh City.

Virological failure and predictors in patients with clinical and immunological failures to first-line ARV regimens in Vietnam