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Methods A retrospective case-control study was conducted at our institution comparing the progression of liver fibrosis in patients with HBV or HDV with and without HIV co-infection. Clinical and laboratory outcomes were recorded. Liver fibrosis was measured by transient elastometry (FibroScan®) and by FIB-4. Values of FibroScan above 9.5 kPa and values over 3.25 for FIB-4 were considered as diagnostic of advanced liver fibrosis (F3–F4 Metavir score estimates). Patients with positive serum HCV-RNA were excluded from this analysis.

Outcome of chronic hepatitis delta in patients with and without HIV infection in the HAART era