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Purpose of the study Co-infection with HBV and HIV-1 is particularly common among patients from sub-Saharan origin, because of the high prevalence of HBV and HIV-1 infection. Differences in HBV subtypes, hepatitis B early antigenemia (HBeAg), and drug resistance mutations can influence the outcome in patients with chronic HBV. The aim of this study was to examine the HBV marker characteristics in HIV/HBV coinfected patients originating from Europe and sub-Saharan Africa attending a Parisian hospital, and to determine risk factors for liver-related morbidity.

Hepatitis B virus (HBV) genotype distribution and lamivudine-resistant mutations in HIV/HBV co-infected patients attending a Parisian hospital