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of results 162 HIV-positive subjects were screened; two patients were excluded because of renal dysfunction. 160 HIV-positive patients (101 male) entered the study and a total of 397 visits were analysed. The median age at all visits was 44 years (range 21–75). Body mass index (BMI) was 24.8 ± 5.1 (men 24.93 ± 0.29, women 24.5 ± 0.48). Patients were without antiretroviral treatment (ART) at 24% of visits and had an undetectable serum HIV load (<50 copies/ ml) at 50% of visits. The median CD4 count was 437 cells/ μl (SD 205.1). CK, creatinine and 3-MH did not correlate with the number of visits.

Measurement of 3-methylhistidine in spot urine from HIV-infected persons: an alternative screening method for muscle protein degradation to serum CK