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Methods The survey on BPCs consisted of two parallel questionnaires, for patient and physician. Ethics Committee approval was received and patient's informed consent was requested to participate. Estimating a 25% BPCs incidence (10% relative error) in the HIV+ Spanish population taking ART (>60,000 pts) and 20% surveys missing, a sample size of 1,020 pts was calculated for a multistage stratified sampling as follows: the 17 Autonomous Communities (ACs) were grouped in 12 strata and 102 physician-sites were allocated among stratum according to their weights [stratum sampling fraction 0.017 (0.014–0.026)]. In each centre, physician was selected by single random sampling, whereas the 10 patients to be surveyed were selected using systematic sampling with random start point from patients visiting the physician in January 2008. Results are shown as weighted rates based on the population per AC over the total surveyed sample (95% CI).

Body physical changes in HIV patients under antiretroviral treatment in Spain