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Purpose of the study Starting HAART at low CD4 counts may be associated with impaired CD4 recovery. However, the factors associated with late presentation and delay of HAART may confound any associations with CD4 response. We studied CD4, VL and clinical outcomes over 4 years of HAART in subjects from the UK CHIC Study who maintained VL suppression for the first year on HAART, stratified by preHAART CD4.

O422 Do the disadvantages of late initiation of HAART persist in patients achieving and maintaining viral load (VL) suppression for a year on HAART?