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Background Early treatment of sepsis has lead to improved outcomes, making early identification of the condition essential. The early warning trigger system TOKS (Tidlig Opsporing af Kritisk Sygdom), including systematically daily recordings of vital signs, was implemented November 1st 2009 throughout Aarhus University Hospital. We hypothesized that the use of TOKS would result in earlier administration of antibiotics for septic patients. The aim of the present study was to compare the degree of appropriately initiated therapy for septic patients admitted to the ICU before and after introduction of TOKS.

Does implementation of an early warning trigger system result in earlier administration of antibiotics for septic patients?