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A 65-year-old woman presented with abdominal pain, weight loss, fatigue, and microcytic anemia. Esophagogastroduodenoscopy, until the second part of duodenum, was normal. Ultrasound and computed tomography demonstrated a solid mass in the distal duodenum. A repeat endoscopy confirmed an ulcerative, intraluminar mass in the third and fourth part of the duodenum. Segmental resection of the third and fourth portion of the duodenum was performed. Histology revealed an adenocarcinoma. On the 4 th  postoperative day, the patient developed severe acute pancreatitis leading to multiple organ failure and died on the 30 th  postoperative day.

Adenocarcinoma of the third and fourth portion of the duodenum: a case report and review of the literature