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Intravascular large B-cell lymphomaB-IVLis listed as a distinct disease entity in the World Health Organization(WHO) classification for lymphoid neoplasms . The disease is rare, and information for its exact frequency among non-Hodgkin lymphomaNHLhas been extremely limited. There have been several reports mainly from Asian countries describing the different disease frequencies . In addition, population of the cases was variously described among these reports. Therefore it is difficult to know the geographical difference in disease frequency, which might be helpful for understanding pathogenesis of disease.

Frequency of intravascular large B-cell lymphoma in Japan: Study of the Osaka Lymphoma Study Group