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Background The cell wall (CW) is one of the most important structures of the yeast cell, accounting for up to 30% of its dry weight. This organelle determines cellular morphology, affords mechanical protection and provides osmotic support. The yeast CW is a dynamic structure susceptible to many modifications, adjusting its composition and thickness to environmental changes. These responses usually involve changes in gene expression, increasing levels of proteins that have protective functions. High hydrostatic pressure (HHP) is a useful model of stress, which causes CW compression [1]. Exploring this process using the model organism Saccharomyces cerevisiae may allow us to understand the mechanisms of yeast stress tolerance in biotechnological processes and it may also helps in searching for effective antifungal drugs, since the CW is a desirable target of action.

Monitoring expression of yeast cell wall protein-encoding genes in response to high hydrostatic pressure