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Currently, therapies using multipotent mescenchymal stem cells (MSCs) are tested clinically for various disorders, including cardiac disease [1]. However, conventional culture media contain fetal bovine serum (FBS) and so the concern about amphixenosis remains. Therefore, developing animal derived factor-free media are desired [2].  We previously reported that rice bran extract (RBE) significantly improved the proliferation of various cell lines and the cellular functions. In this study, we tested the effect of RBE on MSCs in serum-free culture.

Using Rice Bran Extract (RBE) as Supplement for Mescenchymal Stem Cells (MSCs) in Serum-free Culture