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Background Maternal protein restriction during pregnancy promotes several alterations in the progeny. Previous studies showed that androgen/estrogen imbalances during perinatal period, can program prostate cells to develop prostate lesions in adult life after a second insult. This study aimed to investigate prostate diseases susceptibility in adult rat offspring which underwent in utero low protein diet and were chronically exposed to low doses of estrogen and testosterone in adult life.

Undernutrition in utero increases susceptibility to prostate neoplasias in adult rat after steroid exposure