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Background The potential for unintended consequences of the spread of foreign genes (either via vertical or horizontal transfer) and of pleiotropic effects following transgene expression may be enhanced in long-lived forest trees. The COST Action FP0905 will focus on four key aspects related to the biosafety of genetically modified trees (GMTs): (a) analyses of the efficiency of existing gene containment strategies to avoid or if not possible to minimize gene flow; (b) facilitate efforts to develop sitespecific integration of transgenes in tree genomes to minimize variability of transgene expression and pleiotropic effects, (c) evaluate possible methods to monitor GMTs in the whole production chain, and (d) conduct socio-economic and cost/benefit analyses in relation to the use of GMTs in plantations. This Action combines multidisciplinary knowledge generated with transgenic lines of different forest genera (such as, Populus spp., Pinus spp., Eucalyptus spp., Betula spp., Castanea spp., Picea spp., etc.) as well as extensive expertise in correlated topics. The information gained should contribute to strengthen the scientific basis for the execution of the EU policy directives related to transgenic trees intended for cultivation in Europe. The main objective of the COST Action is to evaluate and substantiate the scientific knowledge relevant for GMT biosafety protocols by putting together already existing information generated in various European and Non-EU countries as basis for future EU policy and regulation for the environmental impact assessment and the safe development and practical use of GMTs.

bmc proceedings

COST Action FP0905: Biosafety of forest transgenic trees: improving the scientific basis for safe tree development and implementation of EU policy directives