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Many studies have examined MRSA control measures, but few have been planned prospective single intervention studies in the endemic setting. We asked whether active surveillance & contact precautions (CP) reduced MRSA transmission. We collected & analysed data to avoid confounding (of MRSA acquisition with length of stay) & serial dependence due to colonisation pressure (CoPr) in accordance with ORION guidelines.

Do rapid detection and isolation of colonized patients reduce MRSA spread in the intensive care unit?