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Acalculous cholecystitis has been shown to occur in the context of malarial infection with  Plasmodium vivax  and  Plasmodium falciparum  and requires prompt diagnosis and treatment to prevent complications. To the best of our knowledge this is the first reported case of the disease occurring in a patient infected with  Plasmodium malariae.Case presentation  We report the first case of acalculous cholecystitis associated with  Plasmodium malariae  in a 59-year-old male Nepalese ex-Gurkha soldier. He presented with fever and vomiting and later developed right upper quadrant pain. Abdominal ultrasound and computed tomography scans confirmed acalculous cholecystitis for which he was treated medically with chloroquine, gentamicin and metronidazole. He made a full recovery.    Conclusions  Physicians should be aware that in addition to  Plasmodium vivax  and  Plasmodium falciparum  infections, acalculous cholecystitis can occur in the context of  Plasmodium malariae  infection. Mechanisms for this are discussed but further studies are needed to establish the etiology of this association.

Acalculous cholecystitis occurring in the context of Plasmodium malariae infection: a case report