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One of the bacterial agents that has been found to be associated with colorectal cancer is  Streptococcus bovis , with 13% of infective endocarditis cases caused by this pathogenic species.    Case presentation  We describe the case of a 57-year-old Caucasian man with infiltrating and ulcerating metastatic adenocarcinoma of the sigmoid colon. The patient was receiving second-line chemotherapy treatment and, on the eighth day of the second cycle, he developed a grade IV pancytopenia. We diagnosed a severe sepsis with positive blood cultures for  Streptococcus bovis/gallolyticus  with a secondary endocarditis.    Conclusions  A recent study suggests that the majority of patients affected by colonic cancer have a  Streptococcus bovis/gallolyticus  colonization that becomes apparent as an overt infection only when immunosystem disorders or cardiac valve lesions occur. This correlation is important for involving more specialists in a correct and early diagnosis of this rare, but potentially fatal, complication.

Correlation among Streptococcus bovis, endocarditis and septicemia in a patient with advanced colon cancer: a case report