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Background  Monitoring systemic inflammatory activity during steroid therapy of canine immune-mediated polyarthritis (IMPA) is difficult and mainly relies on clinical signs.    Case presentation  Canine serum C-reactive protein (CRP) was measured serially and blinded during a 27-week follow-up period of a case of  Anaplasma phagocytophilia  induced type II immune-mediated polyarthritis.    Conclusion  WBC was, as expected, observed not to reflect the inflammatory activity during steroid treatment in a clinical useful manner, whereas, CRP is suggested a valuable unbiased marker of inflammatory activity during steroid treatment in this case.

Use of serum C-reactive protein as an early marker of inflammatory activity in canine type II immune-mediated polyarthritis: case report