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Future health and performance management systems should focus on early identification and subsequent prevention of physiological imbalances and production diseases as e.g. subclinical ketosis in dairy cows. Consequently, there is a need for biological indicators that reflectings the status of the dairy cow. ß-hydroxybutyrate (BOHB) in milk is a potential indicator of subclinical and clinical ketosis in dairy cows (1). The concentration of BOHB in plasma is influenced by feedstuffs (2), feeding times (3) and feeding frequency (4), and it is therefore likely that the usefullness of BOHB in milk as an indicator is compromised by these factors. The objectives of the present study were to investigate the diurnal variation and to quantify the effect of a ketogenic ration and the feeding frequency on the concentration of BOHB in milk and BOHB, glucose and non-esterified fatty acids (NEFA) in plasma.

Effects of Glucocorticoids on Immunological Parameters and on Fat Metabolism During Short Time Treatment