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Background Prevalence of non-Hodgkin’s lymphoma (NHL) subgroups throughout Africa, particularly among persons with HIV/AIDS, is unknown but increases in Burkitt lymphoma, plasmablastic lymphoma, and HHV-8 proliferation disorders have been noted. SSALC, an AIDS and Cancer Specimen Resource (ACSR/NCI) project, seeks to define indigenous sub-Saharan NHL subtypes using WHO classification (2008). Omoti (Univ. Benin 2007) defined an overall malignant lymphoma (ML) rate: 13.4/ 100,000 (1990s) including 17% Hodgkin’s disease and 83% NHL but subgroups were not defined. Because regional HIV/AIDS prevalence is high, we subgrouped NHL and reviewed lymph node hyperplasia using stored material from Ahmadu Bello University Teaching Hospital in Zaria, Nigeria, to look for HIV/AIDS-associated lymphoid malignancies.

infectious agents and cancer

Malignant lymphoma subgroups from Zaria, Nigeria, reveal absence of HIV/AIDS-related plasmablastic lymphomas and HHV-8-related lymphoproliferative disorders