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Methods We analyzed the data of HIV-infected adult patients (age > 16 years) who developed a NHL after January 1, 1998. We included patients who were cART naive at inclusion and started cART after January 1, 1998. Only patients who started cART at some point during lifetime were included in the present analysis. cART was defined as regimen with at least three antiretroviral drugs. Patients had to have at least one CD4 cell count measurement after January 1, 1998, and before or within 7 days of NHL diagnosis. Survival and prognostic factors were estimated using crude and adjusted Weibull models, with random-effects accounting for heterogeneity between cohorts.

Survival and prognosis of HIV-associated non-Hodgkin-lymophma in the era of combined anti-retroviral therapy, a European multi-cohort study