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Background Paravalvular regurgitation (PVR) following transcatheter aortic valve implantation (TAVI) is associated with poor survival. The two main valve delivery systems used to date differ in a variety of ways. The primary objective of this study was to perform a systematic review and metaanalysis of studies identifying PVR in patients post TAVI to firstly identify the overall incidence and secondly differentiate between valve types. The secondary objective was to identify additional factors predisposing to PVR to determine whether valve choice is the major determinant of PVR.

Is valve choice the most important determinant of paravalvular leak following TAVI?