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Custodiol cardioplegia is attractive method of myocardial protection, as a single dose provides a long period of preservation. Despite widespread use in Europe, the available data confirming its efficacy is little compared with conventional methods of cardioplegia. Custodiol solution is administered in a single-dose, allowing the operation to be done continuously. This is an advantage over other cardioplegic solutions that may have to be re administered every 20-30 minutes.

The efficacy of custodiol as blood cardioplegia for myocardial protection in adult cardiac surgery