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Methods A 2-arm randomized clinical trial of 250 physicians and patients treated by those physicians. The physician is the unit of randomization. A BPA and order set were developed and embedded in the Epic (Madison, WI) EMR used at 2 hospitals. When an adult patient is admitted to a medical service, a BPA fires if the patient is coded in the EMR as a smoker. For physicians randomized to the intervention, the BPA offers to take the physician to an order set to prescribe tobacco treatment medications and refer the patient to the state smoker’s quitline. Additionally, tobacco use disorder” is added to the patient’s problem list, and an email is sent to the patient’s primary care provider (PCP). In the control arm, a BPA silently fires with no additional actions for the physician. Results Since August 2013, the BPA fired for 4187 patients (1887 intervention, 2300 control). Compared to control arm physicians, intervention physicians were more likely to order tobacco treatment medication (24% v. 9%, P = 0.0001, Fisher’s exact test), populate the problem list with tobacco use disorder (46% v. 4%, P < 0.0001), and make a referral to the state smokers’ quitline (19% v. 0%, P < 0.0001). In addition, intervention physicians sent an email to the patient’s PCP 1876 (99%) times.

Design and implementation of decision support for tobacco dependence treatment in an inpatient electronic medical record