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A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene  SOD2 , rs1789110 near the gene  MBP  and rs722782 near the gene  C8orf42 ) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent population. We investigated the correlation between these variants and advanced age-related macular degeneration for the first time in a Han Chinese cohort; however, no evidence supports these previously identified loci contribute to advanced age-related macular degeneration susceptibility in Chinese population.

Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population