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Digital image analysis (DA) brings new opportunities to enhance breast cancer pathology testing by providing tools to read tissue microscopy-based data in a more precise, accurate, and high-throughput manner. The applications vary from very practical solutions assisting in quantification of biomarker expression to more complex efforts to analyse multi-dimensional data. We present our DA experiments to enhance HER2 immunohistochemistry (IHC) and FISH testing and to explore multiple IHC biomarker variation profiles in breast cancer.

Digital immunohistochemistry: new horizons and practical solutions in breast cancer pathology