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Method We evaluated the report of HIT in Cochrane reviews of unfractionated heparin (UFH) or low molecular weight heparins (LMWH) for thromboprophylaxis after any type of surgery from the 2013 to 2015, period after the publication of a Cochrane review focused on the frequency of HIT in surgical settings. Data extraction aimed to describe how often and accurately HIT was addressed as a specific outcome (primary or secondary) with a precise definition, and how complete was the report of the included clinical trials regarding HIT.

Assessment of main adverse drug reactions in systematic reviews and clinical trials of heparins for surgery prophylaxis