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A recent systematic review on the use of incentives to promote questionnaire return in clinical trials suggest they are effective [1], but not all studies have sufficient funds to use them. Promising an incentive once data are returned can reduce the cost burden of this approach, with possible further cost-savings if the offer were restricted to reminder letters only.  This study aims to evaluate the effect of promising a monetary incentive at first mail out versus a promise on reminder letters only.

Evaluation of the effects of an offer of an incentive on the rate of questionnaire return: a nested RCT