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Contemporary treatments for Oropharyngeal cancer (OPSCC) are associated with a number of debilitating side-effects. Whilst these have a significant impact on the patient’s quality of life, they are often not measured in clinical trials. Additionally there is no standardisation of outcome selection and reporting, even amongst trials of comparable interventions. This reduces the volume of data available for meta-analyses leading to difficulties in both interpreting treatment effect and in making evidence based healthcare decisions. The development of a Core Outcome Set (COS) is proposed to address these problems.

The CONSENSUS Study: Preliminary results of a mixed methods study to develop a core outcome set for late phase clinical trials in Oropharyngeal Cancer