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Motivation Outcome of a bloodstream infection/sepsis (BSI/S) is defined in different ways in different research projects [1]. In this, BSI/S share the characteristics of other fields of medicine; specific issues are related to diversity of causative agents, the clinical focus of infection, severity of comorbid conditions, presence of indwelling devices, multiplicity of affected patient populations, and others [2]. A preliminary list of putative core outcome set (COS) might be:

BISON (Bloodstream Infections and Sepsis Outcomes measurement Network) initiative: an ESGBIS proposal