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Materials and methods We will report the outcome for all 241 patients referred over the past 25 years by tertiary level Obstetricians to our Neurodevelopmental team to either explain the options for treatment of their affected foetus or to provide prognosis for their determination to terminate the pregnancy or carry to term. They include all patients in the cohort and include the following diagnoses: Major brain malformations – 22, Hydrocephalus – 45, Syndromes – 3 and Myelomeningocele (MM) – 171. All but one case with MM were delivered by caesarean section birth before the rupture of amniotic membranes. Analysis was by X2 or Fishers Exact.

Outcome for fetuses with a diagnosis of myelomeningocele, Hydrocephalus and Brain Anomalies