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Background Damage of neural elements in myelomeningocele seems to be progressive during gestation because of amniotic fluid chemical contact. Corticosteroids administration and preterm delivery seem to improve the outcome in gastroschisis (bowel exposition to amniotic fluid) We studied the effect of preterm delivery and corticosteroid treatment in a model of myelomeningocele (MMC) in the rabbit fetus.

Myelomeningocele in fetal rabbit: effect of preterm delivery and corticosteroid treatment