English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Rapid advances in research on antisense transcripts are gradually changing our comprehension of genomic and gene expression aspects of the  Herpesviridae . One such herpesvirus is the human cytomegalovirus (HCMV). Although transcription of the HCMV  UL87  gene has not been specifically investigated, cDNA clones of  UL87  antisense transcripts were found in HCMV cDNA libraries previously. In this study, the transcription of the  UL87  antisense strand was investigated in three clinically isolated HCMV strains.    Results  First, an 800 nucleotides transcript having an antisense orientation to the  UL87  gene was found in a late HCMV cDNA library. Then, the  UL87  antisense transcript was confirmed by Rapid amplification of cDNA ends (RACE) and Northern blot in three HCMV clinical strains. Two ORFs were predicted in the antisense transcript. The putative protein of ORF 1 showed a high degree of conservation among HCMV and other CMV strains.    Conclusion  An 800nt antisense transcript in the  UL87  gene region exists in HCMV clinical strains.

An antisense transcript in the human cytomegalovirus UL87 gene region