English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Measles, caused by measles virus (MeV), is a common infection in children. MeV is a member of the genus  Morbillivirus  and is most closely related to rinderpest virus (RPV), which is a pathogen of cattle. MeV is thought to have evolved in an environment where cattle and humans lived in close proximity. Understanding the evolutionary history of MeV could answer questions related to divergence times of MeV and RPV.  We investigated divergence times using relaxed clock Bayesian phylogenetics. Our estimates reveal that MeV had an evolutionary rate of 6.0 - 6.5 × 10 -4  substitutions/site/year. It was concluded that the divergence time of the most recent common ancestor of current MeV was the early 20 th  century. And, divergence between MeV and RPV occurred around the 11 th  to 12 th  centuries. The result was unexpected because emergence of MeV was previously considered to have occurred in the prehistoric age.  MeV may have originated from virus of non-human species and caused emerging infectious diseases around the 11 th  to 12 th  centuries. In such cases, investigating measles would give important information about the course of emerging infectious diseases.

Origin of measles virus: divergence from rinderpest virus between the 11th and 12th centuries