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Background Participants from the Majengo Commerical Sex Worker Cohort in Nairobi, Kenya have been intensely exposed to HIV for 7-20 years of follow-up, and yet have remained uninfected. Since activated CD4+ T cells are much more susceptible to HIV infection and have been suggested to form the initial focus of mucosal infection, we have conducted a number of studies to characterize the T cell phenotype in the mucosal and systemic compartments of these HIV exposed seronegative women (HESN).

T cell immune quiescence as a contributor to resistance to infection among HIV Exposed Seronegative (HESN) commercial sex workers from Nairobi, Kenya