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Background HIV-1 CRF07_BC descended from subtypes B’ and C represents one of the most prevalent HIV-1 strains in Asia and has been devastating in IDUs for more than a decade in China. Recently, several groups made their effort to address its origin and migration pattern, and had generated several enlightening conclusions, however, the limited available sequences may have restrained the precise depiction of global migration pattern of CRF07_BC. In this study, epidemic evidences and sequences analysis was combined to investigate the transmission linkages among 12 CRF07_BC epidemic regions in China and their tMRCA(time of most recently common ancestor).

A new transmission map of HIV-1 CRF07_BC in China: analysis of sequences from 12 provinces over a decade