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Methods Swarm analysis makes use of the swarm of closely envelope variants that evolve in each HIV-1 infected individual, as a source of naturally occurring and biologically relevant mutations that confer neutralization sensitivity/resistance. Envelopes from clade B and CRF01_AE viruses were tested for neutralization sensitivity/resistance with sera from ENs infected with clade B and CRF01_AE viruses.

Mutations in the V1 domain of Thai CRF01-AE viruses that confer sensitivity/resistance to broadly neutralizing antibodies