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Methods To accomplish this, we performed whole genome transcriptional profiling on sorted epitope-specific CD8 T cells, in the presence and absence of cognate peptide, from a total of 8 B*2705 elite controllers and progressors. Epitope-specific CTLs were isolated using HLA class I tetramers and used to prepare mRNA for evaluation by gene expression profiles using whole genome Illumina bead arrays. Bulk CD8 T cells were used as an internal control for each patient.

Identification of CD8+ T cell host factors involved in HIV control