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The acute encephalitis syndrome has heralded the emergence of multiple virulent pathogens in Australia, including Murray Valley encephalitis, and recently Hendra virus and Australian bat lyssavirus. In Australia, the encephalitis syndrome in humans is not notifiable. The burden of Australian encephalitis hospitalisations and deaths was not known; encephalitis aetiology and trends had not been investigated at population level; and the adequacy of neurological review in hospitalised encephalitis cases to exclude emerging pathogens had not been investigated.

The adequacy of encephalitis surveillance for emerging infectious diseases in Australia