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Background HTLV-1 infection increases susceptibility and severity of tuberculosis. Despite the documentation of a decreased in vitro and in vivo T cells response to mycobacterial antigens, the reasons of the HTLV-1 infection increase the susceptibility and make worse the clinic course of tuberculosis are not understood. For instance, it is not known if HTLV-1 infection increases bacillary load and if severity of tuberculosis is due to the inability of these patients to control bacterial growth. The aim of the present study was to evaluate how HTLV-1 might influence the clinic, bacteriologic and immunologic features of tuberculosis.

Influence of HTLV-1 in the clinic, microbiologic and immunologic features of tuberculosis