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Methods This prospective and observational study was conducted at a referral outclinic in Madrid. All consecutive patients who initiated TDF+FTC+EFV coformulated (Atripla) as a first regim were compared to patients who initiated TDF +FTC (Truvada) plus EFV (Sustiva). Primary outcomes were time to viral suppression and immune recovery, assessed quarterly during regular follow up. Secondary outcomes were classified as drug-related adverse events and AIDS related events. Statistical analyses were realised using the Chi-square and the T-student test for categorical and continuous variables, respectively.

Efficacy and safety of TDF+FTC+EFV in naïve patients initiating HAART; an observational study comparing Atripla Vs Truvada/Sustiva exposure