English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Results The phenotypic analysis showed a significant reduction of CD8+ T naive cells in VI-ART (P = 0.014) and VI-NO ART (P = 0.003) compared to healthy group. The functional analysis revealed that all HIV-infected patients of our study had CD4+ and CD8+ secreting IFN-γ and/or IL-2 in response to our pool of HIV-1 peptides. This recognition involved central memory (TCM, CCR7+CD45RA-), effector memory (TEM, CCR7-CD45RA-), and CD45RA+ effector memory (TEMRA, CCR7-CD45RA+). In the CD4+ compartment the VI-ART group showed the smallest frequency of functional memory in response to our HIV pooled peptides. This observation was more evident in respect to IL-2 producing cells.

P16-53. Distinct subsets of memory T lymphocytes from HIV-1-infected subjects secrete IFN-γ and IL-2 in response to novel CD4+ T-cell HIV-1 epitopes